Nichirin Chemical Industries Ltd., Japan
E.C.G.505 Carmellose Calcium

The main use of Carboxymethylcellulose Calcium is in tablet formulations, where it is used as a binder, diluent, and disintegrant. Although Carboxymethylcellulose Calcium is insoluble in water, it is an effective tablet disintegrant as it swells to several times its original bulk on contact with water. Concentrations up to 15% w/w may be used in tablet formulations; above this concentration, tablet hardness is reduced.

Carboxymethylcellulose Calcium is also used in other applications similarly to Carboxymethylcellulose Sodium; for example, as a suspending or viscosity-increasing agent in oral and topical pharmaceutical formulations.

NS 300 Carmellose

Carboxy Methyl Cellulose –It Is Polycarboxymethylether Of Cellulose, Produced By Lowering The pH Of Sodium CMC By An Acid Treatment. It Is A Super Disintegrant For Tablets Having Lowest Wetting Time Of 3.4 Seconds And Showing Wicking Type Of Disintegrant Mechanism Due To The Property Of Electrostatic Repulsive Force.

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